1. Inhibits TLK1 kinase activity by 60%.
2. Inhibits cellular TLK1 by reduced phosphorylation levels of pRad9 at 5 µM.
3. Cytotoxic towards Prostate cancer and Glioblastoma.
LNCaP- 3.8µM
DU145-19.1 µM
LN227-14.1 µM
4. Suppresses colony formation ability of LNCaP cells when administered along with Bicalutamide.